Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361464 | 0.97 | — | — | |
| SCHEMBL26114001 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL844054 | 0.94 | — | — | |
| Formic Acid SCHEMBL27856318 | 0.84 | NOS1 (0.74) | — | |
| Aminothiazole SCHEMBL27928943 | 0.77 | NOS1 (0.63) | — | |
| SCHEMBL10668923 | 0.74 | NOS1 (0.62) | — | |
| SCHEMBL8627226 | 0.74 | — | — | |
| SCHEMBL27843646 | 0.74 | NOS1 (0.62) | — | |
| SCHEMBL5155088 | 0.74 | — | — | |
| SCHEMBL11657790 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113671193-A | Immunoassay method for L-FABP and assay reagent used for the same | 积水医疗株式会社 | 2021-11-19 | — | — | CN | disclosed |
| EP-3564673-B1 | L-FABP IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD | SEKISUI MEDICAL CO LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| EP-3564673-A1 | L-FABP IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD | Sekisui Medical Co., Ltd. (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-3264083-B1 | L-FABP IMMUNOASSAY METHOD | SEKISUI MEDICAL CO LTD (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-20180246090-A1 | IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD | SEKISUI MEDICAL CO., LTD. (JP) | 2018-08-30 | — | — | US | disclosed |
| US-20180088118-A1 | IMMUNOLOGICAL MEASUREMENT METHOD FOR L-FABP AND MEASUREMENT REAGENT USED IN SAID METHOD | SEKISUI MEDICAL CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |
| EP-3264083-A1 | L-FABP IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD | Sekisui Medical Co., Ltd. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-3264084-A1 | IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD | Sekisui Medical Co., Ltd. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-2513069-B1 | ANTIFUNGAL COMPOUNDS | UNIV LEUVEN KATH (BE) | 2014-10-15 | — | — | EP | disclosed |
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2358682-A2 | ISOQUINOLONE DERIVATIVES AS INHIBITORS OF PLAVIVIRUS REPLICATION | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH LLC | 2010-09-09 | — | — | US | disclosed |
| WO-2010055164-A2 | NOVEL INHIBITORS OF FLAVIVIRUS REPLICATION | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2010-05-20 | — | — | WO | disclosed |
| EP-2144893-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008137816-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20050137239-A1 | Thiazole derivatives | AVON PRODUCTS, INC. | 2005-06-23 | — | — | US | disclosed |
| EP-1543824-A2 | Thiazole derivatives to counter advanced glycation | Avon Products, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| US-4384929-A | THIAZOLE COMPOUND PROVIDES THE SPECIFIED SULFUR CONTENT | OCCIDENTAL CHEMICAL CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |