SCHEMBL20152367

SCHEMBL20152367

NC1=N[C@]2(CCc3cccc(Cl)c3C2)CO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 3/20 1.00
TAAR1 Q96RJ0 3/20 1.00
ADRA2B P18089 2/20 0.54
ADRA2C P18825 2/20 0.54
ADRA1D P25100 2/20 0.54
ADRA1A P35348 2/20 0.54
ADRA1B P35368 2/20 0.54
CYP2D6 P10635 1/20 0.35
PNMT P11086 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
HTR5A P47898 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921322 1.00 ADRA2A (1.00) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7924152 0.84 ADRA2A (0.72) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7917546 0.84 TAAR1 (0.72) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7919747 0.82 ADRA2A (0.69) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7917908 0.81 ADRA2A (0.67) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7926042 0.81 ADRA2A (0.67) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7920323 0.81 ADRA2A (0.67) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7924774 0.80 ADRA2A (0.66) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7929155 0.80 ADRA2A (0.66) ADRA2ATAAR1ADRA2BADRA2CADRA1D
SCHEMBL7911111 0.79 TAAR1 (0.65) ADRA2ATAAR1ADRA2BADRA2CADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
WO-2018087160-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR USE IN CONTROLLING PARASITIC CRUSTACEANS ON FISH I-TECH AB (SE) 2018-05-17 WO disclosed