Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152998 | 0.93 | SLC13A5 (0.40) | MAOBSLC13A5TTRADRA1ATAAR1 | |
| SCHEMBL20152938 | 0.91 | SLC13A5 (0.37) | MAOBSLC13A5TTRADRA1ATAAR1 | |
| SCHEMBL20153024 | 0.87 | ESR2 (0.40) | SLC13A5TTRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20152909 | 0.81 | CYP3A4 (0.36) | MAOBTAAR1ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL20153002 | 0.80 | HSD17B10 (0.39) | ALDH1A1HSD17B10MAPTALOX15 | |
| SCHEMBL20153032 | 0.80 | TYR (0.37) | ALDH1A1HSD17B10MEN1MAPTALOX15 | |
| SCHEMBL20153028 | 0.80 | TYR (0.33) | MAOBALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL20152974 | 0.80 | TYR (0.33) | MAOBKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL178369 | 0.78 | MAOB (0.52) | MAOBTTRTAAR1KDM4EALDH1A1 | |
| SCHEMBL14308495 | 0.77 | TAAR1 (0.66) | MAOBADRA1ATAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |