SCHEMBL2015381

SCHEMBL2015381

Nc1ccc(C(=O)Nc2ccc(N)cc2Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
GAA P10253 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HDAC1 Q13547 3/20 0.51
SERPINE1 P05121 1/20 0.51
MAPK1 P28482 1/20 0.50
CACNA1H O95180 2/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CACNA1B Q00975 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
PYGL P06737 1/20 0.47
PYGM P11217 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886123 0.80 MAPT (0.67) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL3102961 0.80 MAPT (0.67) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL345880 0.80 MAPT (0.63) MAPTCYP1A2CYP2C9CYP2C19GAA
Hydrochloric Acid SCHEMBL3532051 0.79 MAPT (0.65) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL16592552 0.78 MAPT (0.60) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL2276169 0.77 SERPINE1 (0.60) MAPTHDAC1SERPINE1MEN1KMT2A
SCHEMBL27943418 0.77 MAPT (0.67) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL26557770 0.77 MAPT (0.62) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL10604322 0.76 GAA (0.60) MAPTCYP1A2CYP2C9CYP2C19GAA
SCHEMBL26323900 0.76 NR1H4 (0.68) MAPTSMN1; SMN2LMNAMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120315494-A1 Polyamic Acid Resin Composition, Method for Preparing the Same and Polyimide Metal Clad Laminate Using the Same SK INNOVATION CO., LTD. (KR) 2012-12-13 US disclosed
WO-2011078553-A2 POLYAMIC ACID RESIN COMPOSITION, METHOD FOR PREPARING THE SAME AND POLYIMIDE METAL CLAD LAMINATE USING THE SAME SK INNOVATION CO., LTD. (KR) 2011-06-30 WO disclosed