SCHEMBL345880

SCHEMBL345880

COc1cc(N)ccc1NC(=O)c1ccc(N)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.63
GAA P10253 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
KDM4E B2RXH2 2/20 0.62
MAPK1 P28482 1/20 0.62
LMNA P02545 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
AHR P35869 1/20 0.61
CYP1A2 P05177 2/20 0.56
CYP1A1 P04798 1/20 0.56
CYP1B1 Q16678 1/20 0.56
TP53 P04637 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
F10 P00742 1/20 0.53
MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28587110 0.93 ALDH1A1 (0.74) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL28916589 0.91 SMN1; SMN2 (0.64) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL28579628 0.91 KDM4E (0.67) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL3102961 0.91 MAPT (0.67) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL29886123 0.91 MAPT (0.67) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL7291782 0.90 MAPT (0.62) MAPTGAASMN1; SMN2ALDH1A1HPGD
Hydrochloric Acid SCHEMBL3532051 0.90 MAPT (0.65) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL16592552 0.89 MAPT (0.60) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL16592536 0.88 MAPT (0.61) MAPTGAASMN1; SMN2ALDH1A1HPGD
SCHEMBL16392526 0.88 MEN1 (0.58) MAPTGAASMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499951-B Antibacterial toughened polyethylene plastic pipe and preparation method thereof 西藏崇达管业有限公司 2023-02-03 CN claimed
US-10928730-B2 Photosensitive resin composition, and polymer film made therefrom Zhen Ding Technology Co., Ltd. (TW) 2021-02-23 US claimed
US-20150136209-A1 POLYIMIDE LAYER-CONTAINING FLEXIBLE SUBSTRATE, POLYIMIDE LAYER-CONTAINING SUBSTRATE FOR FLEXIBLE SOLAR CELL, FLEXIBLE SOLAR CELL, AND METHOD FOR PRODUCING SAME NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-05-21 US claimed
US-7579134-B2 cover layer comprises polyamic acid precursor curable to an adhesive polyimide base polymer and an ethylenically unsaturated photo-monomer; avoiding unwanted curling of a flexible printed circuit E. I. DUPONT DE NEMOURS AND COMPANY (US) 2009-08-25 US claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
US-7338716-B2 Laminate and process for producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-03-04 US claimed
US-20060210819-A1 Polyimide composite coverlays and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2006-09-21 US claimed
US-20040067349-A1 Laminate and process for producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2004-04-08 US claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed
JP-1245022-A None JP disclosed
EP-4029690-B1 METAL-CLAD LAMINATE FOR FLEXIBLE ELECTRONIC DEVICES, AND FLEXIBLE ELECTRONIC DEVICE USING SAME NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-04-22 EP disclosed
US-12573742-B2 Antenna system, and manufacturing method and design method for same KURARAY CO., LTD. (JP) 2026-03-10 US disclosed
US-12522697-B2 Polyarylene sulfide, and purification method and production method therefor DIC CORPORATION (JP) 2026-01-13 US disclosed
CN-119040979-B Surface treatment process of copper foil, product and application thereof 浙江花园新能源股份有限公司 2025-06-24 CN disclosed
EP-0335337-A2 Flexible base materials for printed circuits NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-10-04 EP disclosed
JP-H01245022-A AROMATIC POLYAMIDEIMIDE RESIN NIPPON STEEL CHEM CO LTD 1989-09-29 JP disclosed
US-4847353-A POLYAMIDEIMIDE COPOLYMERS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-07-11 US disclosed
EP-0297139-A1 FLEXIBLE PRINTED CIRCUIT BOARD AND PROCESS FOR ITS PRODUCTION NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-01-04 EP disclosed
US-4296028-A Pyrazolonyl substituted disazo pigments BASF ITALIA SPA (IT) 1981-10-20 US disclosed
US-4269769-A Diazo compounds obtained by coupling acetoacetanilides with tetrazotized diaminobenzanilides AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12573742-B2 Antenna system, and manufacturing method and design method for same L1CAM, NCSTN, NTRK1 MAPT 1564/4885GAA 4865/4885SMN1; SMN2 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.