Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154185 | 0.84 | KMT2A (0.57) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20886243 | 0.77 | KMT2A (0.49) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20154166 | 0.76 | KMT2A (0.54) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL17965761 | 0.76 | TDP1 (0.61) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL19928034 | 0.75 | MAPT (0.57) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20154182 | 0.75 | KMT2A (0.53) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20154218 | 0.75 | KMT2A (0.49) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL6346314 | 0.75 | ALDH1A1 (0.56) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20886244 | 0.74 | KMT2A (0.46) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL20886230 | 0.74 | KMT2A (0.44) | RAB9AKMT2ANPC1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018839-A1 | ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2021-02-04 | — | — | WO | disclosed |
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018087036-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2018-05-17 | — | — | WO | disclosed |