SCHEMBL201545

SCHEMBL201545

Clc1ccnc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
CYP1A2 P05177 3/20 0.56
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
CYP2C19 P33261 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 1/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NCF1 P14598 1/20 0.56
LOXL2 Q9Y4K0 1/20 0.52
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
HTR1A P08908 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29566907 1.00 MAPT (0.56) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL4471031 0.98 MAPT (0.55) MAPTCYP1A2KDM4EALDH1A1CYP2C9
Ammonia Solution, Strong SCHEMBL2421811 0.98 MAPT (0.55) MAPTCYP1A2KDM4EALDH1A1CYP2C9
Hydrochloric Acid SCHEMBL28052683 0.98 MAPT (0.55) MAPTCYP1A2KDM4EALDH1A1CYP2C9
Butane SCHEMBL8503545 0.90 KDM4E (0.49) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL27589814 0.88 MAPT (0.47) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL8503033 0.87 MAPT (0.46) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL196873 0.84 MAPT (0.58) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL14127360 0.84 MAPT (0.58) MAPTCYP1A2KDM4EALDH1A1CYP2C9
SCHEMBL29971960 0.84 MAPT (0.58) MAPTCYP1A2KDM4EALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2073 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801596-B Photosensitive polyimide resin composition and preparation method and application thereof 深圳先进电子材料国际创新研究院 2025-04-25 CN claimed
CN-116751162-B Quinoline compound, preparation method thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2025-02-28 CN claimed
CN-117945995-A Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof 中国科学院青海盐湖研究所 2024-04-30 CN claimed
CN-114478492-B From CF 3 SO 2 Na-mediated method for cross dehydrogenation and coupling of photocatalytic heteroarene and aliphatic compound bond 南京工业大学 2024-04-09 CN claimed
US-20230407244-A1 MICROBIAL GROWTH-STIMULATING PROTEIN AND METHODS OF USING SAME PARADIGM DIAGNOSTICS, INC. (US) 2023-12-21 US claimed
CN-117003787-A Selective silicon-based-arylation method of olefin compound 南京大学 2023-11-07 CN claimed
CN-116751162-A Quinoline compound, preparation method thereof, pharmaceutical composition and medical application 中国人民解放军军事科学院军事医学研究院 2023-09-15 CN claimed
CN-116751163-A 4-chloroquinoline compound and synthesis method thereof 辽宁大学 2023-09-15 CN claimed
CN-116715602-A Fluorenyl oxalyl diamine compound, derivative and application thereof 华东理工大学 2023-09-08 CN claimed
US-11732285-B2 Selective enrichment media and uses thereof PARADIGM DIAGNOSTICS, INC. (US) 2023-08-22 US claimed
CN-1017244-B Process for preparing triazolyl quinoline derivatives ALKALOIDA WEGYESZETI GYAR (HU) 1992-07-01 CN claimed
CN-1043717-A Cephalosporin compound TANABE SEIYAKU CO (JP) 1990-07-11 CN claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0205362-B1 QUINOLYL GLYCINAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE AS PSYCHOTROPES SANOFI (FR) 1989-12-20 EP claimed
US-4795621-A CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND SHIN NISSO KAKO CO., LTD. (JP) 1989-01-03 US claimed
CN-86103997-A The preparation method of triazolyl quinoline derivative class 1987-12-30 CN claimed
EP-0221947-A1 TRIAZOLYL QUINOLINE DERIVATIVES. ALKALOIDA VEGYESZETI GYAR (HU) 1987-05-20 EP claimed
WO-1986006721-A1 TRIAZOLYL QUINOLINE DERIVATIVES ALKALOIDA VEGYÉSZETI GYÁR (HU) 1986-11-20 WO claimed
US-4277607-A Process for the preparation of 4-chloroquinolines ROUSSEL UCLAF (FR) 1981-07-07 US claimed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed