Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694172 | 1.00 | OGA (0.41) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL23635267 | 0.88 | OGA (0.44) | OGAPDE4DLMNASMN1; SMN2PIM1 | |
| SCHEMBL17359884 | 0.88 | OGA (0.44) | OGAPDE4DLMNASMN1; SMN2PIM1 | |
| SCHEMBL13471607 | 0.88 | OGA (0.44) | OGAPDE4DLMNASMN1; SMN2PIM1 | |
| SCHEMBL8819151 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL24760374 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL12526525 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL22065208 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL13265415 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR | |
| SCHEMBL13102723 | 0.87 | OGA (0.39) | OGAPDE4DLMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10441564-B2 | Fructose analogs and their combinations as anti-cancer agents | Jia, Wei (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180133192-A1 | Fructose analogs and their combinations as anti-cancer agents | JIA, WEI | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133192-A1 | Fructose analogs and their combinations as anti-cancer agents | ALDOA, FBP1, MPI | OGA 297/4885PDE4D 3572/4885LMNA 3090/4885 |
| US-10441564-B2 | Fructose analogs and their combinations as anti-cancer agents | ALDOA, FBP1, MPI | OGA 255/4885PDE4D 3405/4885LMNA 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.