Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 20/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 17/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155212 | 0.94 | SLC5A2 (0.52) | SLC5A2SLC5A1CYP3A4 | |
| SCHEMBL20154885 | 0.88 | SLC5A1 (0.48) | SLC5A2SLC5A1 | |
| SCHEMBL20154938 | 0.87 | SLC5A2 (0.49) | SLC5A2SLC5A1 | |
| SCHEMBL20155549 | 0.87 | SLC5A2 (0.66) | SLC5A2SLC5A1 | |
| SCHEMBL20154944 | 0.85 | SLC5A2 (0.52) | SLC5A2SLC5A1 | |
| SCHEMBL20155230 | 0.85 | SLC5A2 (0.49) | SLC5A2SLC5A1 | |
| SCHEMBL20155267 | 0.81 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL26764163 | 0.81 | SLC5A2 (0.52) | SLC5A2SLC5A1CYP3A4 | |
| SCHEMBL22590705 | 0.80 | SLC5A2 (0.75) | SLC5A2SLC5A1 | |
| SCHEMBL20154888 | 0.79 | SLC5A2 (0.49) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |