Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155586 | 0.87 | BRD4 (0.36) | BRD4PDE4B | |
| SCHEMBL20155419 | 0.80 | BRD4 (0.33) | BRD4P2RX3 | |
| SCHEMBL20155585 | 0.74 | BRD4 (0.34) | BRD4PDE4B | |
| SCHEMBL20155085 | 0.70 | BRD4 (0.34) | BRD4PDE4B | |
| SCHEMBL20155684 | 0.69 | BRD4 (0.35) | BRD4PDE4B | |
| SCHEMBL20118620 | 0.67 | BRD4 (0.37) | BRD4P2RX3 | |
| SCHEMBL21915864 | 0.67 | BRD4 (0.68) | BRD4 | |
| SCHEMBL19931061 | 0.66 | BRD4 (0.47) | BRD4 | |
| SCHEMBL25043211 | 0.66 | BRD4 (0.43) | BRD4 | |
| SCHEMBL19931377 | 0.66 | BRD4 (0.54) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |