Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654996 | 0.71 | BRD4 (0.54) | BRD4 | |
| SCHEMBL20094747 | 0.69 | BRD4 (0.56) | BRD4 | |
| SCHEMBL19930642 | 0.69 | BRD4 (0.38) | BRD4HTR2AHTR2CHTR2BPDE10A | |
| SCHEMBL20155051 | 0.67 | BRD4 (0.35) | BRD4P2RX3 | |
| SCHEMBL19931012 | 0.67 | BRD4 (0.37) | BRD4PTGER1 | |
| SCHEMBL21915864 | 0.67 | BRD4 (0.68) | BRD4 | |
| SCHEMBL20155419 | 0.66 | BRD4 (0.33) | BRD4P2RX3 | |
| SCHEMBL19931061 | 0.66 | BRD4 (0.47) | BRD4 | |
| SCHEMBL19931229 | 0.66 | BRD4 (0.49) | BRD4 | |
| SCHEMBL19931063 | 0.66 | BRD4 (0.49) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081475-A1 | BROMODOMAIN AND EXTRA-TERMINAL PROTEIN INHIBITOR COMBINATION THERAPY | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-05-03 | — | — | WO | disclosed |