Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155724 | 0.83 | GSK3B (0.32) | GSK3B | |
| SCHEMBL20155610 | 0.80 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL20155732 | 0.79 | GSK3B (0.30) | GSK3B | |
| SCHEMBL20155488 | 0.72 | KDM4E (0.42) | — | |
| SCHEMBL20155615 | 0.71 | GSK3B (0.34) | GSK3B | |
| SCHEMBL27497898 | 0.65 | — | — | |
| SCHEMBL15637351 | 0.61 | ADORA2A (0.40) | — | |
| SCHEMBL27335401 | 0.59 | NPC1 (0.32) | — | |
| SCHEMBL9185865 | 0.58 | AXL (0.53) | GSK3B | |
| SCHEMBL30231227 | 0.58 | AXL (0.53) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |