Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154994 | 0.85 | CHEK1 (0.60) | CHEK1 | |
| SCHEMBL20154917 | 0.81 | CHEK1 (0.63) | CHEK1 | |
| SCHEMBL22617554 | 0.75 | CHEK1 (0.55) | CHEK1 | |
| SCHEMBL21299965 | 0.73 | ROCK2 (0.44) | CHEK1 | |
| SCHEMBL21299958 | 0.72 | CHEK1 (0.56) | CHEK1 | |
| SCHEMBL20154920 | 0.69 | CHEK1 (0.69) | CHEK1 | |
| SCHEMBL20154886 | 0.69 | CHEK1 (0.70) | CHEK1 | |
| SCHEMBL21299912 | 0.68 | TYRO3 (0.46) | CHEK1 | |
| SCHEMBL24158266 | 0.65 | CHEK1 (0.64) | CHEK1 | |
| SCHEMBL20155271 | 0.65 | CHEK1 (0.66) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086547-A1 | 2-SUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE, AND PREPARATION AND APPLICATION THEREOF | 浙江大学 | 2018-05-17 | — | — | WO | disclosed |