Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598551 | 0.98 | ALDH1A1 (0.77) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL8199849 | 0.97 | ALDH1A1 (0.74) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7961779 | 0.94 | ALDH1A1 (0.70) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL15854998 | 0.92 | ALDH1A1 (0.68) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL3898192 | 0.91 | CA12 (0.70) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL3905679 | 0.89 | CA12 (0.72) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL472226 | 0.88 | CA12 (0.70) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7095728 | 0.88 | CA12 (0.66) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7203889 | 0.88 | CA12 (0.70) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL6130663 | 0.86 | ALDH1A1 (0.60) | ALDH1A1CA12CA2CA9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486544-B2 | Manganese chelates and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2016-11-08 | — | — | US | disclosed |
| EP-2512524-B1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2016-10-05 | — | — | EP | disclosed |
| EP-2512524-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE Healthcare AS (NO) | 2012-10-24 | — | — | EP | disclosed |
| US-20120244081-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2012-09-27 | — | — | US | disclosed |
| WO-2011073371-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-06-23 | — | — | WO | disclosed |
| EP-0882055-B1 | POLYAZAMACROCYCLOFLUOROMONOALKYLPHOSPHONIC ACIDS, AND THEIR COMPLEXES, FOR USE AS CONTRAST AGENTS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0570574-B1 | BICYCLOPOLYAZAMACROCYCLOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION, CONJUGATES AND RADIOPHARMACEUTICALS | DOW CHEMICAL CO (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5834456-A | MAGNETIC RESONANCE IMAGING AND IN VIVO SPECTROSCOPY OF FLUORINE; SENSITIVITY, TISSUE DISTRIBUTION | THE DOW CHEMICAL COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5750660-A | CONTRAST AGENTS; MEDICAL DIAGNOSIS | THE DOW CHEMICAL COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5739294-A | MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5480990-A | COMPLEXES WITH GADOLIUM, MANGANESE AND IRON IONS AND JOINED TO ANTIBODIES FOR MEDICAL DIAGNOSIS | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5428139-A | Anticarcinogenic agents | THE DOW CHEMICAL COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| WO-1994026313-A1 | BICYCLOPOLYAZAMACROCYCLOCARBOXYLIC ACID COMPLEXES, THEIR CONJUGATES, PROCESSES FOR THEIR PREPARATION, AND USE AS CONTRAST AGENTS | THE DOW CHEMICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244081-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | MAG, MPI, MB | ALDH1A1 4435/4885CA12 223/4885CA2 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.