SCHEMBL20155360 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	BRD4	O60885	18/20	0.49

▸	BRDT	Q58F21	1/20	0.48

▸	KDM4E	B2RXH2	1/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	ALDH1A1	P00352	1/20	0.38

▸	CYP1A2	P05177	1/20	0.38

▸	CYP2D6	P10635	1/20	0.38

▸	MAPT	P10636	1/20	0.38

▸	CYP2C9	P11712	1/20	0.38

▸	HPGD	P15428	1/20	0.38

▸	CYP2C19	P33261	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	PDE7A	Q13946	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20155554	0.89	BRD4 (0.42)	BRD4BRDTALDH1A1HPGD
SCHEMBL20155002	0.87	BRD4 (0.49)	BRD4
SCHEMBL20155411	0.87	BRD4 (0.47)	BRD4
SCHEMBL20155702	0.86	BRD4 (0.40)	BRD4BRDT
SCHEMBL20155028	0.84	BRD4 (0.41)	BRD4KDM4EALDH1A1
SCHEMBL21904826	0.84	BRD4 (0.65)	BRD4BRDT
SCHEMBL20155006	0.83	BRD4 (0.46)	BRD4
SCHEMBL20155069	0.81	BRD4 (0.75)	BRD4BRDT
SCHEMBL20155476	0.77	BRD4 (0.43)	BRD4
SCHEMBL20155478	0.77	BRD4 (0.43)	BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018086604-A1	NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF	山东罗欣药业集团股份有限公司	2018-05-17	—	—	WO	disclosed