Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155291 | 0.87 | BRD4 (0.42) | BRD4BRD2BRD3BRDTMAPK14 | |
| SCHEMBL20155445 | 0.84 | BRD4 (0.39) | BRD4BRD2BRD3BRDT | |
| SCHEMBL20155443 | 0.82 | BRD4 (0.54) | BRD4BRD2BRD3BRDT | |
| SCHEMBL20155038 | 0.80 | BRD4 (0.42) | BRD4BRD2BRD3BRDTMAPK14 | |
| SCHEMBL20155515 | 0.79 | BRD4 (0.43) | BRD4MAPK14 | |
| SCHEMBL20155692 | 0.78 | SLC6A2 (0.34) | BRD4 | |
| SCHEMBL20155007 | 0.78 | SLC6A2 (0.35) | BRD4 | |
| SCHEMBL20155068 | 0.78 | BRD4 (0.41) | BRD4BRD2BRD3BRDTMAPK14 | |
| SCHEMBL20155531 | 0.78 | BRD4 (0.41) | BRD4MAPK14 | |
| SCHEMBL20155690 | 0.76 | BRD4 (0.38) | BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |