Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155291 | 0.91 | BRD4 (0.42) | BRD4 | |
| SCHEMBL20155692 | 0.87 | SLC6A2 (0.34) | SLC6A2SLC6A3BRD4SLC6A4 | |
| SCHEMBL20155186 | 0.85 | TDO2 (0.31) | — | |
| SCHEMBL20155356 | 0.84 | ALDH1A1 (0.34) | BRD4SLC6A4 | |
| SCHEMBL20155383 | 0.84 | BRD4 (0.35) | SLC6A2SLC6A3BRD4SCN8ASCN10A | |
| SCHEMBL20155038 | 0.83 | BRD4 (0.42) | BRD4 | |
| SCHEMBL20155068 | 0.82 | BRD4 (0.41) | BRD4 | |
| SCHEMBL20155487 | 0.81 | BRD4 (0.33) | BRD4 | |
| SCHEMBL20155030 | 0.81 | SCN9A (0.34) | — | |
| SCHEMBL20155531 | 0.81 | BRD4 (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |