Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155425 | 0.85 | SOS1 (0.46) | GAAALDH1A1HTTTDP1IDO1 | |
| SCHEMBL20155101 | 0.83 | ALDH1A1 (0.47) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155604 | 0.79 | NPC1 (0.43) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155589 | 0.76 | BCL6 (0.47) | GAAALDH1A1HTTTDP1MAPK1 | |
| SCHEMBL4058691 | 0.75 | GAA (0.46) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155614 | 0.75 | IDO1 (0.40) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155496 | 0.73 | SOS1 (0.42) | ALOX15GAAALDH1A1IDO1KMT2A | |
| SCHEMBL20155629 | 0.72 | ALDH1A1 (0.47) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155710 | 0.72 | ALDH1A1 (0.51) | ALOX15GAAALDH1A1HTTTDP1 | |
| SCHEMBL20155415 | 0.72 | SLC6A2 (0.44) | GAAALDH1A1TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |