Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TST | Q16762 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HAT1 | O14929 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155597 | 0.89 | GSR (0.48) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL27460346 | 0.86 | MEN1 (0.63) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL21743935 | 0.86 | MEN1 (0.63) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL20155594 | 0.83 | KDM4E (0.38) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL29375626 | 0.78 | GSR (0.51) | KDM4EMEN1USP2KMT2AMAPT | |
| SCHEMBL14176774 | 0.78 | GSR (0.51) | KDM4EMEN1USP2KMT2AMAPT | |
| SCHEMBL24201806 | 0.77 | MEN1 (0.74) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL19424100 | 0.77 | MEN1 (0.74) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL20155598 | 0.77 | MEN1 (0.74) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL30935958 | 0.75 | MEN1 (0.67) | KDM4EMEN1USP2CASP1BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087413-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2018-05-17 | — | — | WO | disclosed |