Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HAT1 | O14929 | 2/20 | 0.43 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TST | Q16762 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155596 | 0.89 | KDM4E (0.46) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL20155594 | 0.78 | KDM4E (0.38) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL21743935 | 0.75 | MEN1 (0.63) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL27460346 | 0.75 | MEN1 (0.63) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL24201806 | 0.74 | MEN1 (0.74) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL20155598 | 0.74 | MEN1 (0.74) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL19424100 | 0.74 | MEN1 (0.74) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL30935958 | 0.72 | MEN1 (0.67) | GSRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL10368365 | 0.70 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPTHTT | |
| SCHEMBL29778192 | 0.69 | CYP1A2 (0.45) | GSRKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087413-A1 | RUTHENIUM COMPLEXES FOR TREATING CANCER WHICH COMPRISES CANCER STEM CELLS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2018-05-17 | — | — | WO | disclosed |