Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 12/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281637 | 0.79 | SUCNR1 (0.42) | SUCNR1BDKRB1KDM4EMEN1LMNA | |
| SCHEMBL21281670 | 0.78 | KMT2A (0.45) | SUCNR1BDKRB1KDM4EMEN1LMNA | |
| SCHEMBL21281674 | 0.77 | SUCNR1 (0.41) | SUCNR1BDKRB1KDM4EMEN1LMNA | |
| SCHEMBL20156049 | 0.77 | SUCNR1 (0.41) | SUCNR1BDKRB1KDM4EMEN1LMNA | |
| SCHEMBL30829495 | 0.75 | F2 (0.46) | FLT1KDRL3MBTL1KDM4EMEN1 | |
| SCHEMBL27406008 | 0.75 | SUCNR1 (0.50) | SUCNR1BDKRB1KDM4EMEN1LMNA | |
| SCHEMBL20156356 | 0.74 | ALOX15 (0.39) | L3MBTL1KDM4ELMNAKMT2AALOX15 | |
| SCHEMBL6258525 | 0.73 | F2 (0.43) | FLT1KDRL3MBTL1KDM4EMEN1 | |
| SCHEMBL20156357 | 0.73 | MAPK1 (0.44) | FLT1KDRL3MBTL1KDM4EMEN1 | |
| SCHEMBL20156353 | 0.73 | CXCR4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |