SCHEMBL20156410

SCHEMBL20156410

C=C(C)c1cc(-c2nnc(CC)[nH]2)c(C2CC(F)(F)C2)cc1C

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30281116 0.71 FASN (0.34) FASN
SCHEMBL30280749 0.65 TTR (0.37)
SCHEMBL12686763 0.64 FASN (0.61) FASN
SCHEMBL12489252 0.62 FASN (0.41) FASN
SCHEMBL12489359 0.61 FASN (0.44) FASN
SCHEMBL12488020 0.60 FASN (0.42) FASN
SCHEMBL18432284 0.60 ALDH1A1 (0.37)
SCHEMBL19113325 0.60 FASN (0.33) FASN
SCHEMBL12488288 0.60 FASN (0.42) FASN
SCHEMBL12489277 0.59 FASN (0.39) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089904-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2018-05-17 WO disclosed