Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 4/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432260 | 0.84 | PDK2 (0.37) | HTR2APTGDR2PTGDRNPC1ALDH1A1 | |
| SCHEMBL20156420 | 0.83 | JAK2 (0.31) | — | |
| SCHEMBL18432496 | 0.78 | PDK2 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18432463 | 0.73 | MAPT (0.42) | — | |
| SCHEMBL10174527 | 0.72 | PTGDR2 (0.41) | HTR2APTGDR2PTGDRALDH1A1 | |
| SCHEMBL19559130 | 0.72 | MAPT (0.34) | HTR2APTGDR2PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL18432288 | 0.72 | PDK2 (0.40) | ALDH1A1FASN | |
| SCHEMBL10174627 | 0.70 | FASN (0.45) | FASN | |
| SCHEMBL19113325 | 0.70 | FASN (0.33) | HTR2APTGDR2FASN | |
| SCHEMBL18869770 | 0.69 | NOTUM (0.34) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |