Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156431 | 0.83 | HTR2A (0.33) | — | |
| SCHEMBL18432260 | 0.78 | PDK2 (0.37) | — | |
| SCHEMBL18432463 | 0.75 | MAPT (0.42) | — | |
| SCHEMBL18432496 | 0.72 | PDK2 (0.41) | — | |
| SCHEMBL19113325 | 0.72 | FASN (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL18869770 | 0.71 | NOTUM (0.34) | JAK2JAK1JAK3 | |
| SCHEMBL20156462 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL20156606 | 0.70 | FASN (0.37) | — | |
| SCHEMBL12489077 | 0.69 | GABRP (0.36) | JAK2JAK1JAK3 | |
| SCHEMBL20156411 | 0.69 | JAK2 (0.35) | JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |