Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 9/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.46 |
| ▸ | SI | P14410 | 9/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156571 | 0.87 | GAA (0.47) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL27984123 | 0.85 | KCNMA1 (0.55) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL4209963 | 0.72 | KCNMA1 (0.64) | GAASMN1; SMN2RAB9AKCNMA1TSHR | |
| SCHEMBL4497575 | 0.71 | GAA (0.56) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL8262277 | 0.71 | GAA (0.49) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL24060749 | 0.70 | KCNMA1 (0.53) | GAASMN1; SMN2RAB9AKCNMA1MGAM | |
| SCHEMBL19092972 | 0.70 | KCNMA1 (0.61) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL13772814 | 0.70 | KCNMA1 (0.57) | GAASMN1; SMN2RAB9AKCNMA1MGAM | |
| SCHEMBL24633525 | 0.70 | KCNMA1 (0.53) | GAASMN1; SMN2RAB9ANPC1KCNMA1 | |
| SCHEMBL18899456 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1KCNMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |