Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015051 | 0.87 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2012749 | 0.84 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL2014992 | 0.82 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2051297 | 0.82 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2054212 | 0.80 | HCRTR1 (0.60) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2015191 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2054210 | 0.80 | HCRTR1 (0.60) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2011910 | 0.80 | HCRTR1 (0.69) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL2017894 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL2052571 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |