SCHEMBL2015660

SCHEMBL2015660

CCCCCCCCC=CCCCCCCC=C1OC(=O)C1CCCCCCC=CCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 1/20 0.41
TYR P14679 2/20 0.40
ABHD16A O95870 1/20 0.40
EPHX2 P34913 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
CDC25C P30307 1/20 0.39
MGLL Q99685 1/20 0.39
PPARG P37231 3/20 0.38
TERT O14746 3/20 0.37
MAPT P10636 2/20 0.37
BLM P54132 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FABP4 P15090 2/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18614709 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL18064497 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL2015657 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL2021152 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL2015658 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL18614706 1.00 ALDH1A1 (0.47) ALDH1A1TSHRFAAHTRPV1TYR
SCHEMBL18614617 0.95 TYR (0.43) ALDH1A1TSHRTYRABHD16AEPHX2
SCHEMBL18614691 0.95 TYR (0.43) ALDH1A1TSHRTYRABHD16AEPHX2
SCHEMBL18614707 0.95 TYR (0.43) ALDH1A1TSHRTYRABHD16AEPHX2
SCHEMBL20561502 0.95 TYR (0.43) ALDH1A1TSHRTYRABHD16AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180334571-A1 WATER REPELLENT COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2018-11-22 US disclosed
EP-3347421-A1 WATER REPELLENT COMBINATIONS Janssen Pharmaceutica N.V. (BE) 2018-07-18 EP disclosed
US-9796665-B2 Ceramide derivatives having agonistic effects on epidermal cannabinoid receptors, and pharmaceutical or cosmetic composition containing same NEOPHARM CO., LTD. (KR) 2017-10-24 US disclosed
WO-2017042120-A1 WATER REPELLENT COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2017-03-16 WO disclosed
US-20160272578-A1 NOVEL CERAMIDE DERIVATIVES HAVING AGONISTIC EFFECTS ON EPIDERMAL CANNABINOID RECEPTORS, AND PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING SAME NEOPHARM CO., LTD. (KR) 2016-09-22 US disclosed
US-8632659-B2 Paper sizing composition HERCULES INCORPORATED (US) 2014-01-21 US disclosed
EP-2513373-B1 PAPER SIZING COMPOSITION HERCULES INC (US) 2013-10-09 EP disclosed
EP-1299488-B1 COMPOSITIONS FOR IMPARTING DESIRED PROPERTIES TO MATERIALS HERCULES INC (US) 2013-09-04 EP disclosed
EP-2513373-A2 PAPER SIZING COMPOSITION Hercules Incorporated (US) 2012-10-24 EP disclosed
WO-2011075633-A2 PAPER SIZING COMPOSITION HERCULES INCORPORATED (US) 2011-06-23 WO disclosed
US-20110146926-A1 Paper Sizing Composition THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2011-06-23 US disclosed
US-7317053-B1 Compositions for imparting desired properties to materials HERCULES INCORPORATED (US) 2008-01-08 US disclosed
EP-1299488-A2 COMPOSITIONS FOR IMPARTING DESIRED PROPERTIES TO MATERIALS HERCULES INCORPORATED (US) 2003-04-09 EP disclosed
WO-2002008514-A2 METHOD OF MAKING SIZING EMULSION AND SIZING EMULSION HERCULES INCORPORATED (US) 2002-01-31 WO disclosed
WO-2002004133-A2 COMPOSITIONS FOR IMPARTING DESIRED PROPERTIES TO MATERIALS HERCULES INCORPORATED (US) 2002-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272578-A1 NOVEL CERAMIDE DERIVATIVES HAVING AGONISTIC EFFECTS ON EPIDERMAL CANNABINOID RECEPTORS, AND PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING SAME CNR1, CNR2, CERS2 ALDH1A1 4586/4885TSHR 1698/4885FAAH 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.