Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265623 | 0.89 | ARG1 (0.39) | ARG1ARG2 | |
| SCHEMBL16309657 | 0.89 | ARG1 (0.39) | ARG1ARG2 | |
| SCHEMBL895474 | 0.86 | ARG1 (0.57) | ARG1ARG2 | |
| SCHEMBL895475 | 0.86 | ARG1 (0.57) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894179 | 0.85 | ARG1 (0.56) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894177 | 0.85 | ARG1 (0.56) | ARG1ARG2 | |
| SCHEMBL28817969 | 0.75 | ARG1 (0.44) | ARG1ARG2TLR2 | |
| SCHEMBL28825397 | 0.75 | ARG1 (0.44) | ARG1ARG2TLR2 | |
| Hydrochloric Acid SCHEMBL28256875 | 0.74 | PRCP (0.35) | ARG1ARG2PRCPS1PR2S1PR4 | |
| Hydrochloric Acid SCHEMBL28256845 | 0.74 | PRCP (0.35) | ARG1ARG2PRCPS1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089490-A1 | ARGINASE INHIBITOR COMBINATION THERAPIES | CALITHERA BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |