Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422585 | 0.74 | KDM4E (0.49) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL29269626 | 0.74 | DDAH1 (0.43) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL29269640 | 0.74 | MEN1 (0.39) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL30422091 | 0.74 | KDM4E (0.49) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL30421508 | 0.74 | MEN1 (0.39) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL30421459 | 0.74 | DDAH1 (0.43) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL30422552 | 0.73 | KDM4E (0.33) | KDM4EL3MBTL1NPSR1RXFP1MEN1 | |
| SCHEMBL29269785 | 0.73 | MEN1 (0.38) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL30421497 | 0.73 | MEN1 (0.38) | KDM4EL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL12778696 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |