Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088832 | 0.90 | DRD4 (0.54) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL30406641 | 0.82 | AR (0.59) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL829177 | 0.82 | AR (0.65) | DRD4DRD2GRM5ARALDH1A1 | |
| SCHEMBL23277098 | 0.81 | KDM4E (0.58) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL21572676 | 0.81 | DRD4 (0.48) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL2077260 | 0.81 | GRM5 (0.51) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL2077261 | 0.81 | ADRA2C (0.56) | DRD4DRD2GRM5DRD3AR | |
| SCHEMBL7528396 | 0.80 | AR (0.62) | DRD4DRD2GRM5ARALDH1A1 | |
| SCHEMBL31388194 | 0.80 | AR (0.62) | DRD4DRD2GRM5ARALDH1A1 | |
| SCHEMBL7524105 | 0.80 | AR (0.62) | DRD4DRD2GRM5ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |