Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157224 | 0.89 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20157232 | 0.88 | CYP1A2 (0.30) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20157047 | 0.87 | — | — | |
| SCHEMBL20157024 | 0.86 | — | — | |
| SCHEMBL20157338 | 0.84 | POLB (0.33) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20157000 | 0.82 | MEN1 (0.41) | — | |
| SCHEMBL20156884 | 0.82 | CYP1A2 (0.34) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20157538 | 0.81 | CYP1A2 (0.30) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20157194 | 0.80 | — | — | |
| SCHEMBL20157310 | 0.78 | SMN1; SMN2 (0.32) | CYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |