Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29882451 | 0.90 | CHRNB2 (0.50) | CHRNB4CHRNA3GRM1CHRNB2CHRNA4 | |
| SCHEMBL20071406 | 0.79 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL26048823 | 0.79 | GRM1 (0.47) | GRM1HCRTR1HCRTR2 | |
| SCHEMBL20064022 | 0.79 | GRM1 (0.47) | GRM1HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL23607827 | 0.78 | CHRNB4 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL29535557 | 0.78 | CHRNB4 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL25222660 | 0.78 | CHRNB4 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL23019809 | 0.75 | KMT2A (0.51) | GRM1HCRTR1HCRTR2 | |
| SCHEMBL20004006 | 0.75 | KMT2A (0.51) | GRM1HCRTR1HCRTR2 | |
| SCHEMBL23046561 | 0.75 | GRM1 (0.44) | GRM1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |