Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142524 | 0.84 | MTOR (0.44) | MTORRPTORMLST8GRIN2BSIGMAR1 | |
| SCHEMBL20140766 | 0.79 | MTOR (0.46) | MTORRPTORMLST8SIGMAR1 | |
| SCHEMBL20139962 | 0.77 | MTOR (0.55) | MTORRPTORMLST8GRIN2BTACR3 | |
| SCHEMBL20157087 | 0.76 | MTOR (0.50) | MTORRPTORMLST8TACR3 | |
| SCHEMBL20157079 | 0.76 | MTOR (0.50) | MTORRPTORMLST8TACR3 | |
| SCHEMBL20157176 | 0.76 | MTOR (0.50) | MTORRPTORMLST8TACR3 | |
| SCHEMBL20140200 | 0.75 | MTOR (0.59) | MTORRPTORMLST8TACR3 | |
| SCHEMBL20140246 | 0.72 | MTOR (0.57) | MTORRPTORMLST8 | |
| SCHEMBL20140719 | 0.72 | MTOR (0.57) | MTORRPTORMLST8 | |
| SCHEMBL20140883 | 0.72 | SIGMAR1 (0.44) | MTORRPTORMLST8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |