SCHEMBL20157652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20157981	0.92	POLB (0.50)	KDM4CNPC1MAPTL3MBTL1ALDH1A1
	SCHEMBL21555619	0.87	KDM4C (0.47)	KDM4CNPC1PPARGHDAC3HDAC1
	SCHEMBL20157358	0.86	KDM4C (0.60)	KDM4CMAPTL3MBTL1ALDH1A1GAA
	SCHEMBL20157655	0.83	MAPT (0.55)	KDM4CMAPTL3MBTL1ALDH1A1GAA
	SCHEMBL21351883	0.79	KDM4C (0.51)	KDM4CHDAC3HDAC1HDAC2MAPT
	SCHEMBL14994042	0.79	KDM4E (0.50)	KDM4CL3MBTL1ALDH1A1GAAHSD17B10
	SCHEMBL20157455	0.79	APLNR (0.49)	KDM4CNPC1MAPTL3MBTL1ALDH1A1
	SCHEMBL21362495	0.78	APLNR (0.51)	KDM4CNPC1MAPTL3MBTL1ALDH1A1
	SCHEMBL20157651	0.78	APLNR (0.41)	KDM4CHDAC3HDAC1HDAC2HDAC6
	SCHEMBL20157650	0.78	APLNR (0.51)	KDM4CNPC1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.