Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137037 | 0.83 | KDM4E (0.38) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| SCHEMBL20157948 | 0.83 | CETP (0.36) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| Hydrochloric Acid SCHEMBL20137043 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| SCHEMBL29561187 | 0.81 | FFAR4 (0.39) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| SCHEMBL20137089 | 0.81 | FFAR4 (0.39) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| SCHEMBL20158307 | 0.80 | CETP (0.40) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| Hydrochloric Acid SCHEMBL29560707 | 0.80 | FFAR4 (0.39) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| Hydrochloric Acid SCHEMBL20137048 | 0.80 | FFAR4 (0.39) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| Trifluoroacetic Acid SCHEMBL29561105 | 0.79 | PPARG (0.39) | KDM4EALDH1A1NR1H3NR1H2PPARG | |
| SCHEMBL20137009 | 0.78 | MGLL (0.36) | KDM4EALDH1A1NR1H3NR1H2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | KDM4E 984/4885ALDH1A1 4349/4885NR1H3 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.