SCHEMBL20158162

SCHEMBL20158162

CC(C)(C)OC(=O)NOCCOCCOCCOCCNC(=O)CCCCCCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
GLP1R P43220 8/20 0.37
CYP3A4 P08684 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16315843 0.88 MEN1 (0.47) EPHX2CA1CA2TDP1CYP3A4
SCHEMBL3703562 0.88 MEN1 (0.47) EPHX2CA1CA2TDP1CYP3A4
SCHEMBL15084748 0.84 TDP1 (0.41) CA1CA2TDP1MAOAMAOB
SCHEMBL31298558 0.84 MEN1 (0.48) EPHX2CA1CA2TDP1CYP3A4
SCHEMBL31296192 0.84 TDP1 (0.51) EPHX2CA1CA2TDP1CYP3A4
SCHEMBL21293834 0.84 TDP1 (0.51) EPHX2CA1CA2TDP1GLP1R
SCHEMBL3486237 0.83 TDP1 (0.43) EPHX2CA1CA2TDP1CYP3A4
SCHEMBL14258504 0.82 ADORA1 (0.37) CA1CA2GLP1RMEN1GAA
SCHEMBL20450590 0.82 GLP1R (0.47) TDP1GLP1RMEN1KMT2A
SCHEMBL23601923 0.81 CA1 (0.37) EPHX2CA1CA2TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11135306-B2 Antibody-drug conjugates CHO Pharma Inc. (TW) 2021-10-05 US disclosed
US-20190328895-A1 ANTIBODY-DRUG CONJUGATES CHO Pharma Inc. (TW) 2019-10-31 US disclosed
US-20180133340-A1 ANTIBODY-DRUG CONJUGATES CHO Pharma Inc. (TW) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190328895-A1 ANTIBODY-DRUG CONJUGATES CSGALNACT1, ADCY1, NEU1 EPHX2 3578/4885CA1 402/4885CA2 510/4885
US-20180133340-A1 ANTIBODY-DRUG CONJUGATES CSGALNACT1, ST6GAL1, PA2G4 EPHX2 3956/4885CA1 469/4885CA2 552/4885
US-11135306-B2 Antibody-drug conjugates CSGALNACT1, ST6GAL1, PA2G4 EPHX2 3956/4885CA1 469/4885CA2 552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.