Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.58 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.58 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159019 | 0.90 | MTOR (0.59) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20159153 | 0.89 | MTOR (0.61) | MTORRPTORMLST8PPARGSLC27A1 | |
| SCHEMBL20140500 | 0.87 | MTOR (0.67) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20159267 | 0.85 | MTOR (0.56) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20140543 | 0.85 | MTOR (0.65) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20159110 | 0.84 | MTOR (0.57) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20159030 | 0.84 | MTOR (0.62) | MTORRPTORMLST8HTR7ALDH1A1 | |
| SCHEMBL20159289 | 0.83 | MTOR (0.63) | MTORRPTORMLST8HTR7MAPT | |
| SCHEMBL20140534 | 0.83 | MTOR (0.63) | MTORRPTORMLST8HTR7MAPT | |
| SCHEMBL20159067 | 0.83 | MTOR (0.65) | MTORRPTORMLST8HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |