Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 12/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870147 | 0.87 | FOLH1 (0.53) | FOLH1CYP1A2SLC1A3SLC1A2 | |
| SCHEMBL6384195 | 0.84 | CYP1A2 (0.64) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL28552864 | 0.84 | KISS1R (0.53) | FOLH1CYP1A2SLC1A3SLC1A2 | |
| SCHEMBL19815017 | 0.84 | FOLH1 (0.56) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL28747078 | 0.84 | FOLH1 (0.50) | FOLH1SLC1A3SLC1A2 | |
| SCHEMBL31544401 | 0.84 | FOLH1 (0.50) | FOLH1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6845392 | 0.83 | CYP1A2 (0.61) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL10028833 | 0.83 | CYP1A2 (0.61) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL25840968 | 0.83 | CYP1A2 (0.61) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL5059822 | 0.83 | FOLH1 (0.57) | FOLH1CYP1A2GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113502305-B | Method for synthesizing (R) -isobutyl glutarate monoamide by utilizing recombinant imidinase | 台州学院 | 2024-01-30 | — | — | CN | claimed |
| CN-113502305-A | Method for synthesizing (R) -isobutyl glutaric acid monoamide by using recombinant imide enzyme | 台州学院 | 2021-10-15 | — | — | CN | claimed |
| CN-110483317-A | The preparation method and application of high-purity 3- isobutylglutaric acid dimethyl ester | HUANGGANG LUBAN PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-106278931-A | The preparation method of 3 isobutylglutaric acid monoamides | 苏州英诺欣医药科技有限公司 | 2017-01-04 | — | — | CN | claimed |
| EP-0828704-B1 | METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER LAMBERT CO (US) | 2002-03-13 | — | — | EP | claimed |
| EP-0828704-A1 | METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER-LAMBERT COMPANY (US) | 1998-03-18 | — | — | EP | claimed |
| US-5616793-A | Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1997-04-01 | — | — | US | claimed |
| WO-1996038405-A1 | METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER-LAMBERT COMPANY (US) | 1996-12-05 | — | — | WO | claimed |
| CN-113502305-B | Method for synthesizing (R) -isobutyl glutarate monoamide by utilizing recombinant imidinase | 台州学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-114740101-B | Method for detecting impurities in pregabalin pharmaceutical composition | 德全药品(江苏)股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114740101-A | Method for detecting impurities in pregabalin pharmaceutical composition | 永信药品工业（昆山）股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113502305-A | Method for synthesizing (R) -isobutyl glutaric acid monoamide by using recombinant imide enzyme | 台州学院 | 2021-10-15 | — | — | CN | disclosed |
| CN-113502305-A | Method for synthesizing (R) -isobutyl glutaric acid monoamide by using recombinant imide enzyme | 台州学院 | 2021-10-15 | — | — | CN | disclosed |
| CN-113502305-A | Method for synthesizing (R) -isobutyl glutaric acid monoamide by using recombinant imide enzyme | 台州学院 | 2021-10-15 | — | — | CN | disclosed |
| US-5886024-A | ENZYME INHIBITOR FOR TREATING ARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA | BAYER CORPORATION (US) | 1999-03-23 | — | — | US | disclosed |
| US-5874473-A | OSTEOPOROSIS; ANTIARTHRITIC AGENTS | BAYER CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-5861428-A | ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, INFLAMMATION, OSTEOPENIAS, TEMPERO | BAYER CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| US-5861427-A | ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, CONDITIONS LEADING TO INFLAMMATORY | BAYER HEALTHCARE LLC | 1999-01-19 | — | — | US | disclosed |
| US-5859047-A | ANTIARTHRITIC AGENTS, NERVOUS SYSTEM DISORDERS | BAYER CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| US-5854277-A | Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors | BAYER CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |