Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159442 | 0.85 | NAMPT (0.40) | NAMPT | |
| SCHEMBL20159185 | 0.85 | NAMPT (0.46) | NAMPT | |
| SCHEMBL20159540 | 0.83 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20142989 | 0.83 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20138884 | 0.83 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20159433 | 0.80 | NAMPT (0.59) | NAMPT | |
| SCHEMBL20159251 | 0.76 | NAMPT (0.39) | NAMPTROCK2 | |
| SCHEMBL10770760 | 0.75 | CYP1A2 (0.53) | TP53 | |
| SCHEMBL20159147 | 0.74 | NAMPT (0.39) | NAMPTROCK2 | |
| SCHEMBL20159253 | 0.74 | NAMPT (0.39) | NAMPTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |