Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 16/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159147 | 0.88 | NAMPT (0.39) | NAMPTTAS1R3TAS1R1TAS1R2ROCK2 | |
| SCHEMBL20142989 | 0.87 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20159540 | 0.87 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20138884 | 0.87 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20159455 | 0.86 | ROCK2 (0.54) | NAMPTROCK2 | |
| SCHEMBL20159742 | 0.85 | NAMPT (0.36) | NAMPTROCK2 | |
| SCHEMBL20159436 | 0.83 | HDAC1 (0.37) | NAMPT | |
| SCHEMBL20159128 | 0.82 | NAMPT (0.38) | NAMPTROCK2 | |
| SCHEMBL20159164 | 0.82 | NAMPT (0.42) | NAMPTROCK2 | |
| SCHEMBL20138906 | 0.81 | ROCK2 (0.53) | NAMPTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |