Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23504822 | 0.84 | SMN1; SMN2 (0.32) | PPARG | |
| SCHEMBL20139332 | 0.83 | EPAS1 (0.40) | EPAS1 | |
| SCHEMBL20159311 | 0.77 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL23504765 | 0.77 | BTK (0.36) | EPAS1 | |
| SCHEMBL20160067 | 0.76 | EPAS1 (0.33) | EPAS1 | |
| SCHEMBL20139093 | 0.74 | EPAS1 (0.38) | EPAS1 | |
| SCHEMBL20138718 | 0.71 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL20143018 | 0.69 | EPAS1 (0.37) | EPAS1PPARG | |
| SCHEMBL20138671 | 0.69 | EPAS1 (0.36) | EPAS1PPARG | |
| SCHEMBL29623268 | 0.69 | EPAS1 (0.39) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538516-B1 | PHENOXYTRIAZOLES | HOFFMANN LA ROCHE (CH) | 2021-06-16 | — | — | EP | disclosed |
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |