Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194220 | 0.79 | KMT2A (0.39) | GRM2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL14668837 | 0.73 | GRM2 (0.32) | GRM2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL23504747 | 0.68 | — | — | |
| SCHEMBL20159330 | 0.64 | MEN1 (0.31) | SMN1; SMN2 | |
| SCHEMBL21218007 | 0.64 | CSNK2A1 (0.44) | ADORA2AADORA2BADORA1 | |
| SCHEMBL4406803 | 0.63 | MAPT (0.44) | GRM2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31437829 | 0.61 | GRM2 (0.38) | GRM2SMN1; SMN2 | |
| SCHEMBL29067966 | 0.61 | ADORA2A (0.39) | GRM2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL16911879 | 0.60 | GRM2 (0.33) | GRM2SMN1; SMN2 | |
| SCHEMBL21217940 | 0.60 | SMN1; SMN2 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |