Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142951 | 0.79 | KMT2A (0.39) | KMT2A | |
| SCHEMBL23264381 | 0.74 | — | — | |
| SCHEMBL20159263 | 0.73 | — | — | |
| SCHEMBL22667104 | 0.64 | APAF1 (0.41) | LMNAMAPTHTT | |
| SCHEMBL20159598 | 0.64 | GRM2 (0.33) | SMN1; SMN2 | |
| SCHEMBL24977403 | 0.63 | GFER (0.35) | LMNAMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL16911239 | 0.63 | — | — | |
| SCHEMBL3194220 | 0.63 | KMT2A (0.39) | KMT2ASMN1; SMN2 | |
| SCHEMBL15273754 | 0.62 | ALDH1A1 (0.37) | MAPT | |
| SCHEMBL31267051 | 0.62 | DGAT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |