Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783322 | 0.96 | MAPK1 (0.53) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL10265288 | 0.96 | POLB (0.53) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL13746318 | 0.92 | GAA (0.61) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL17625632 | 0.92 | L3MBTL1 (0.57) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL13783325 | 0.92 | L3MBTL1 (0.61) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL13745743 | 0.90 | GAA (0.64) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL8257182 | 0.90 | GAA (0.64) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL14472719 | 0.90 | KDM5A (0.45) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL13783326 | 0.90 | L3MBTL1 (0.64) | L3MBTL1GAATSHREPHX2MAPK1 | |
| SCHEMBL23583243 | 0.89 | MAPK1 (0.63) | L3MBTL1GAATSHREPHX2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089695-A1 | TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USE | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |