SCHEMBL20159826

SCHEMBL20159826

CNC(=O)C(CNC(=O)/C=C/Br)CNC(=O)/C=C/Br

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GFPT1 Q06210 1/20 0.33
CNR2 P34972 5/20 0.33
CNR1 P21554 3/20 0.33
PPARG P37231 2/20 0.33
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20159682 0.77 TSHR (0.46)
SCHEMBL10769556 0.76 CNR2 (0.51) CNR2CNR1PPARGPPARDPPARA
SCHEMBL20159831 0.71 USP2 (0.31)
SCHEMBL7754362 0.68 KISS1R (0.42)
SCHEMBL7093098 0.66
SCHEMBL18122766 0.64
SCHEMBL7161352 0.62 CNR2 (0.58) GFPT1CNR2CNR1PPARGPPARD
SCHEMBL10763922 0.61 CNR2 (0.53) CNR2CNR1PPARGPPARDPPARA
SCHEMBL6871426 0.61
SCHEMBL18756319 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3888691-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2021-10-06 EP disclosed
WO-2018086139-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2018-05-17 WO disclosed