Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159848 | 0.86 | BRD4 (0.61) | BRD4 | |
| SCHEMBL20160294 | 0.77 | BRD4 (0.43) | BRD4 | |
| SCHEMBL20160047 | 0.73 | BRD4 (0.59) | BRD4BRD2BRD3BRDT | |
| SCHEMBL20160287 | 0.72 | BRD4 (0.61) | BRD4 | |
| SCHEMBL20159993 | 0.63 | BRD4 (0.62) | BRD4 | |
| SCHEMBL20159925 | 0.63 | BRD4 (0.62) | BRD4 | |
| SCHEMBL16766082 | 0.62 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15069508 | 0.62 | BRD4 (1.00) | BRD4BRD2BRD3BRDT | |
| SCHEMBL30543331 | 0.61 | PIK3CD (0.49) | — | |
| SCHEMBL30915419 | 0.60 | KDR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |