SCHEMBL20160077 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	BRD4	O60885	20/20	0.49

▸	EP300	Q09472	2/20	0.47

▸	BRD2	P25440	2/20	0.45

▸	BRD3	Q15059	2/20	0.45

▸	BRDT	Q58F21	2/20	0.45

▸	ADORA2B	P29275	1/20	0.45

▸	TSPO	P30536	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20160260	0.92	BRD4 (0.51)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160080	0.90	BRD4 (0.54)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160345	0.90	BRD4 (0.50)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160257	0.87	BRD4 (0.50)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160006	0.87	BRD4 (0.55)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160044	0.87	BRD4 (0.54)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160269	0.87	BRD4 (0.51)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160092	0.87	BRD4 (0.51)	BRD4EP300BRD2BRD3BRDT
SCHEMBL20160087	0.86	BRD4 (0.40)	BRD4BRD2BRDT
SCHEMBL20160233	0.86	BRD4 (0.55)	BRD4EP300BRD2BRD3BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018086585-A1	NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF	山东罗欣药业集团股份有限公司	2018-05-17	—	—	WO	disclosed