Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160299 | 0.87 | BRPF1 (0.38) | BRD4BRPF1TRIM24BRD1TAF1 | |
| SCHEMBL20160077 | 0.86 | BRD4 (0.49) | BRD4BRD2BRDT | |
| SCHEMBL20159918 | 0.83 | BRPF1 (0.53) | BRD4BRPF1TRIM24BRD1TAF1 | |
| SCHEMBL20160236 | 0.82 | BRD4 (0.43) | BRD4BRD2BRDTMAPT | |
| SCHEMBL20160322 | 0.82 | BRD4 (0.39) | BRD4BRD2BRDT | |
| SCHEMBL20160270 | 0.81 | BRD4 (0.42) | BRD4BRD2BRDT | |
| SCHEMBL20159911 | 0.81 | BRD4 (0.43) | BRD4BRD2CREBBP | |
| SCHEMBL20159910 | 0.78 | NPC1 (0.39) | BRD4BRPF1KCNQ3KCNQ2NPC1 | |
| SCHEMBL20160260 | 0.78 | BRD4 (0.51) | BRD4BRD2BRDT | |
| SCHEMBL20160345 | 0.76 | BRD4 (0.50) | BRD4BRD2BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |