Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 12/20 | 0.80 |
| ▸ | BTK | Q06187 | 14/20 | 0.73 |
| ▸ | TXK | P42681 | 14/20 | 0.73 |
| ▸ | JAK3 | P52333 | 12/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162007 | 0.89 | ITK (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161488 | 0.85 | BTK (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161688 | 0.85 | BTK (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161954 | 0.85 | ITK (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161917 | 0.84 | BTK (0.81) | ITKBTKTXKJAK3 | |
| SCHEMBL20161861 | 0.83 | JAK3 (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161730 | 0.83 | JAK3 (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL20161227 | 0.83 | JAK3 (1.00) | ITKBTKTXKJAK3 | |
| SCHEMBL24467262 | 0.81 | ITK (0.83) | ITKBTKTXKJAK3 | |
| SCHEMBL20161947 | 0.81 | ITK (0.83) | ITKBTKTXKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |