Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434957 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL7738031 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL12872570 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL15043900 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL5523660 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL1593467 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL1154515 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL1154638 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL20888696 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 | |
| SCHEMBL12872828 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7PREPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323818-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |